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Panhematin.
View a tutorial that explains how to prepare and administer Panhematin.
Dr. Karl Anderson discusses the pathophysiology of the disorder and explains a key diagnostic test.
Watch the video
Read this case study about a 19-year-old woman who presented to an emergency department with acute abdominal pain.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/MedWatch, or call 1-800-FDA-1088.
PANHEMATIN (hemin for injection) is a prescription medication used to relieve repeated attacks of acute intermittent porphyria related to the menstrual cycle in affected women.
Signs and symptoms of acute intermittent porphyria such as pain, high blood pressure, rapid heart beat, abnormal mental status and mild to progressive neurologic signs (including seizures and paralysis) may be controlled in some patients with this disorder.
Similar findings have been reported in other patients with acute intermittent porphyria, porphyria variegata and hereditary coproporphyria. PANHEMATIN is not indicated in porphyria cutanea tarda.
PANHEMATIN does not cure acute intermittent porphyria. After stopping PANHEMATIN treatment, symptoms usually return, although some patients experience a period without symptoms.
PANHEMATIN should only be used by doctors experienced in the management of porphyrias in hospitals where the recommended clinical and laboratory diagnostic and monitoring practices are available.
PANHEMATIN therapy should be considered after an appropriate period of alternate therapy (i.e., 400 g glucose/day for 1 to 2 days).
PANHEMATIN is not for patients known to be allergic to this drug. PANHEMATIN is made from human blood and therefore may contain agents that can cause infections, such as viruses, that can cause disease including Creutzfeldt-Jakob disease.
Drugs such as estrogens, barbituric acid derivatives, steroid-like drugs, and blood thinners should be avoided during PANHEMATIN therapy. Your doctor should monitor your iron levels if you receive multiple courses of PANHEMATIN.
Reversible kidney shutdown has occurred with high doses. Because vein inflammation has been reported after administering PANHEMATIN through small arm veins, a large arm vein or a central line should be used.
For more information, please see Full Prescribing Information including Boxed Warning at www.lundbeckus.com.
PHT117R1
Panhematin is a registered trademark of Lundbeck.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/MedWatch, or call 1-800-FDA-1088.
PANHEMATIN (hemin for injection) is indicated for the amelioration of recurrent attacks of acute intermittent porphyria temporally related to the menstrual cycle in susceptible women.
Manifestations such as pain, hypertension, tachycardia, abnormal mental status and mild to progressive neurologic signs may be controlled in selected patients with this disorder.
Similar findings have been reported in other patients with acute intermittent porphyria, porphyria variegata and hereditary coproporphyria. PANHEMATIN is not indicated in porphyria cutanea tarda.
PANHEMATIN should only be used by physicians experienced in the management of porphyrias in hospitals where the recommended clinical and laboratory diagnostic and monitoring techniques are available.
PANHEMATIN therapy should be considered after an appropriate period of alternate therapy (i.e., 400 g glucose/day for 1 to 2 days).
PANHEMATIN is contraindicated in patients with known hypersensitivity to this drug. PANHEMATIN is made from human blood and therefore may contain infectious agents, such as viruses, that can cause disease including Creutzfeldt-Jakob disease.
Drugs such as estrogens, barbituric acid derivatives, steroid metabolites, and anticoagulants should be avoided during PANHEMATIN therapy. Increased levels of iron and serum ferritin have been reported in post-marketing experience; therefore, physicians should monitor iron and serum ferritin in patients receiving multiple administrations of PANHEMATIN.
Reversible renal shutdown has occurred with administration of excessive doses. Because phlebitis has been reported after administration of PANHEMATIN through small arm veins, a large arm vein or a central venous catheter should be utilized for administration.
For more information, please see Full Prescribing Information including Boxed Warning at www.lundbeckus.com.
PHT116R1
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